Showing posts with label wellbutrin sr 150 mg. Show all posts
Showing posts with label wellbutrin sr 150 mg. Show all posts

Tuesday, February 1, 2011

Can you take wellbutrin 300mg at once

can you take wellbutrin 300mg at once


can you take wellbutrin 300mg at once


Question about Wellbutrin SR/XL (Bupropion SR/XL ...

Yes they are pretty much the same, the SR is sustained release, and some people take it twice a day, the XL at 300mg, only has to be taken once a day, it releases even slower into your system. ...

Prozac Then Wellbutrin Xl, Now What? (For Major Depression And ...

I was switched over to 150 mg of Wellbutrin XL (now taking 300mg) and 1 mg Ativan for sleep. Thethe Wellbutrin is making me feel very aggressive and agitated a lot of the time, making me feel worse. I started going to a psychologist ... I do take Wellbutrin 300XL and its been great for the depression. Once it gets into your system and reach the therapuetic point, you should be feeling much better. It could take from 4 to 6 wks before that happen, or maybe a little longer. ...

still here, still fighting

I take Welbutrin and can't get any sleep either so I take Zopiclone for that. Every now and then it wears off so I have to stop it for a while....Seems like we build up a tolerance for anything that gives us sleep....Used to take seroquel and effexor. ... I'm sorry to hear that you're having a rough go of it littlejoe. I too hope your next P.doc appt. is soon. What form of Wellbutrin are you taking? The 300mg XL once daily or the regular 150mg tablets twice daily? ...

What is the difference between SR and XL when talking about ...

I have bupropion HCL XL 300 mg (substituted for: wellbutrin XL 300 mg) and Budeprion SR 150 mg (substituted for: wellbutrin SR 150 mg). I have been prescribed budeprion SR 150mg twice a day but I am running low with no refills and not a ... You can not cut XL pill in half. Wellbutrin Sr (which im on too) is a ~8 hour release, so usually taken twice a day. Welbutrin XL is a 24 hour release so you take it once a day. You DO NOT cut, crush or chew extended relese tablets or ...

Wellbutrin? | Weight Loss Drugs

I had done some research before taking it and did notice that it can actually cause anxiety in some people. After taking it about a month I looked into it again on the internet and found one website that said you can test positive for an amphetamine like substance in the blood. ... For example I take 300mg of wellbutrin but I worked my way up to that, a friend of mine was taking the same briefly but his general MD started him at 300mg which is NOT a good thing. ...

Why did my doctor give me 300mg of Wellbutrin that made me have ...

Because you had a seizure with Wellbutrin, you should not try it again. Luckily, there are many other drugs out there that you can try instead. It sounds like your neurologist was doing just what he/she should of… starting you with a low 150mg dose for a few days (usually 3, ... if your doctor knew that 300 mg of Wellbutrin was going to do that to you he wouldn't have prescribed it. Now you know not to take it. You just have a low tolerance to that particular drug. ...

How long does it take for Wellbutrin 300 mg to start working ...

And anyone who begins treatment of depression needs to stay in contact with their doc, so that if one doesn't work, or stops working he/she can try something else. The only downside of Welbutrin is that it is extremely expensive. ... Most antidepressants take 6-8 weeks to completely kick in. Depending on what kind of Wellbutrin you're taking, SR or XL, the time of day does matter. If you only have to take Wellbutrin SR once a day, take it in the morning. ...

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I can never reach my doctor, so do you think this is okay ...

I'm taking budeprion xl (wellbutrin) 150mg right now. And I know it's available in 300mg and I think that dosage would be much better for me. Do you think I can go ahead and start taking 2 until I can get to my doctor to ask her to ...




























































Monday, January 17, 2011

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Wellbutrin or bupropion has several side effects some of which include nausea, dry mouth, cough, constipation, sweating, joint pain, blurred vision, strange taste or dizziness. In most cases, these symptoms subside with time. ...

Prozac Then Wellbutrin Xl, Now What? (For Major Depression And ...

What you seem to be experiencing as well are some start up side effects of Wellbutrin. This should subside over time. But sense your psychologist has given you the diagnosis of Social Anxiety Disorder, your doctor will prescribe you an ...

Are There Any Good Alternatives To Wellbutrin In Terms Of Side ...

I was on Wellbutrin for about a month. It was good in terms of alleviating depression and wasn't bad in helping me focus, but taking anything abo...

Wellbutrin Research and Vendor Information

Wellbutrin is generally well tolerated. Side effects of Wellbutrin may include dry mouth, headache, increased sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision. If these effects persist or worsen, ...

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Wellbutrin? | Weight Loss Drugs

okay so i'm going to start going on wellbutrin tomorrow.and i just wanted to know what should i expect from the side effects.i have to take it during the day because it causes insomina at night and i'm gonna be at work tomorrow in the ...

Wellbutrin? | Weight Loss Drugs

Lglarsen52 says: January 12, 2011 at 12:07. I take a combination of Wellbutrin & Lexapro & am very pleased with the results. One of the side effects of Wellbutrin is appetite suppression, so you probably will lose weight. ...

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Bipolar and Psychosis, please help!?

I am taking bupropion hydrochloride (slow release) as prescribed by my doctor for depression. The problem is, someday I feel normal and someday depressed (even if medicine is continued). I have taken this for three months so far. At present I feel as if I am extremely tired so that I can not even think any complicated issue. Is there anybody who had taken this and felt like this? Is it necessary to take vitamin B supplement with this medicine? I always have suffered side effects while taking this medicine, which include: tremor in hands, anxiety, etc. I am considering discontinuation of this medicine. However, I would like to know experience of others before that.



What are the side effects of Bupropion (Wellbutrin, Zyban)?

I have been on Wellbutrin and have had this tingling cold feeling running down my leg as if my foot is asleep but it is not. I noticed this started to happen over a period of 5 weeks use of Wellbutrin SR.I have talked to my doctor about potentially switching over to something more calming to the nerves.Prozac for anxiety depression as well as prevention of overeating because I heard it curbs your appetite.Another choice is Norityptaline which I have tried but still felt melancholy around a 100 mg dose. However the Norityptaline helped me sleep easier but feel a little out of it in the morning. I was also concerned about any potential side effects on the heart.Any suggestions would be greatly appreciated.



Prozac or Norityptaline for anxiety and depression?

I have been taking wellbutrin for 2 weeks now. I was weined of citalorpam because it caused major restless legs. I went to my dr the other day and told him the wellbutrin was making me go crazy...dizzy, light headed, nausea, irritable and way more anxiety. He gave me effexor which i used to take a long time ago to try and counter act the way it makes me feal. The reason for going off the effexor was the sexual side effects so this is supposed to make me feal better but im not.Im not sure when i can get into my dr again and I really want to just stop the wellbutrin any advice?I hate this fealing its not normal.



wellbutrin makes me feal jittery should I go off it?

I am SO FRUSTRATED with how much weight I've gained since I started Seroquel a few years ago. I am diagnosed with hypomania and am currently on 600 mg Seroquel and 250 mg Wellbutrin since I had a terrible depressive episode after my last manic episode over a year ago. I was originally misdiagnosed with major depression and prescribed Celexa, but I am quite sure I experienced mania before going on Celexa. But even on Seroquel, with the Celexa I kept going manic. But now I feel like the Seroquel is making me depressed, but I don't think my psychiatrist will approve me to even gradually go off Seroquel. I would like to try naturopathic treatment, because I am concerned about side effects and long term effects from pharmaceuticals.Unfortunately I can't just up and say I want an new psychiatrist. In my city you are considered lucky to see a psychiatrist at all, and you can't pick and choose. The first time I told my GP I wanted a referral to a psychiatrist he actually laughed at me and said I was looking at at least 6 months to a year wait list. The next time I went back with a list of psychiatrists who were taking new patients, which I got from my worker at the Canadian Mental Health Association, and even though I was crying before he even came into the office, he still hummed and hawed, and finally in desperation I told him I felt like I wasn't getting the help I needed, and then he got his butt in gear and within 15 minutes I had an appointment with my psychiatrist. Unfortunately i have had a hard time with her, and feel like she doesn't really give a sh!t about me as a person.Oh, and the other thing that p!sses me off is that she runs her practice out of her home, is not centrally located, and lives near the outskirts of the city, which means it takes me over an hour by bus to get there. And then she sips on juice or tea or whatever she wants, but is rude enough to not offer any to her patients, which I think is extremely rude. If she won't offer any to her patients, she shouldn't be drinking it in front of them, as far as I'm concerned. She's just tucked away in her nice, safe, rich neighbourhood and and is totally disconnected from the realities of mental illness and poverty.Jerry, just to be totally clear, I have a diagnosis of hypomania from a psychiatrist.



Anyone with bipolar successfully go off of Seroquel and/or go med free?

I attempted suicide back in 2004. I haven't been able to cry in the past 3 years. I have had 3 members of my family pass away over those last 3 years and, I have suffered through clinical Bipolar Depression, hard friendship issues, and my parent's divorce... to list a few. You'd think with all of this I would be able to cry, but I can't. I want to cry so much at times, but all I can get are watery eyes, and I can never manage to shed tears. At all of those family member's funerals, with everyone balling their eyes out... but I couldn't do anything but sit there feeling as awful as everyone else is, but I couldn't show it. I'm on medication, 400MG of Lamictal and 200MG Wellbutrin so my Bipolar depression is under control. I wasn't able to cry BEFORE I was ever put on meds...so it's not a side effect. When I get teary eyed, I keep trying to shed a tear...but it never happens. Look I'm a 17 year old guy, and I don't believe that BS that guys stop crying as they age. I don't hold back tears at all and I openly express my emotions, but I just can't manage to cry. Is there possibly a physical illness that maybe prevents me from doing so? I loved those members of my family VERY much...so it's not like they didn't mean enough to me for me to cry. And when I can't cry, I get angry about it...What's wrong with me?*I have been seeing a therapist for the past 7yrs. And see her on a biweekly basics.*I am seeing a psychiatrist. On a monthly med check basics. Or more often if needed.



Is there and illness that prevents me from crying? Why can't I cry?

I am trying to quit smoking. A few years ago my Dr. wrote me a script for Zyban and it worked quite well and quickly (in about two or three days i had no real desire to smoke). Unfortunatley the Zyban caused panic attacks, etc so i had to stop taking it.Fast forward a few years (about a week and a half ago actually). I am still trying to quit. I figured I'd bite the bullet and try Zyban again. Unfortunately, it is not covered by my insurance company anymore. My Dr. instead gave me a script for Wellbutrin XL 150. He said to take one every other day (remembering the issues I had with the Zyban). I did this for a week and it did not seem to be working. I fealt no side effects (which is good i guess) but I was still smoking like a chimney (maybe even more). I am now taking it daily (for the last 5 days now). I am starting to feel the side affects of the med now but have not noticed any less desire to smoke. I am smoking just as much. I am wondering if I should give it another couple of days or is 150 not enough (I believe with the Zyban the daily dosage was 300). Any thoughts?P.S. I also take 20mg of cipralex (Lexapro) a day. I hope that this is not affecting the Wellbutrin performance. I don't think it should as they target different chemicals in the brain, but who knows...



Wellbutrin XL 150 and smoking cessation?

I am at the end of trying many antidepressants. I am now trying Wellbutrin SR 150 mg 2x/day as a final effort to help me feel lessbleak and hopeless. I have been on wellbutrin sr 150mg 2x/day (generic) and wonder if others have tried this medication at this dose and 4 weeks is just not enough time for it to take effect?I have tried many depression medications without much success.Lexapro- (max dose for a month and a half)Zoloft- (max dose for a month and a half)Effexor- (max dose for two months)Paxil- for a very short periodAmitriptylineNortriptylineprozac (max dose for a two months)Pristiq max dose, felt pretty good but started to worry about side effects of increased cholesterol as with many of these medications is a consideration. Any advice or experiences is greatly appreciated



I have been on Wellbutrin SR for four weeks should I feel better at this point?

Hi,Over the last several months I have been receiving treatment for depression and/or borderline personality disorder [no official decision has been made]. This treatment has involved the use of antidepressants [among other things] however I have not really been responding to them. In fact, I can honestly say none of them have done anything for me. So far I have been put on [in the following order]:Prozac [20mg then 40mg]Citalopram [Don't remember the dosage]Mirtazapine [15mg then 30mg]Wellbutrin XL [150mg then 300mg]I've also been given Seroquel, Clonazepam and Olanzapine in combination with a few of themI have taken each for at least a month before being switched.I am currently taking Wellbutrin and Olanzapine.I can honestly say I have gotten nothing out of any of these medications other than a dent in my bank account. I have been on Wellbutrin and Olanzapine for a month and a half now and I have no idea why these things don't work for me. I have read of others who have had 'life changing' experiences from the use of any one of these drugs and I don't get anything. I don't even suffer any of the alleged side effects they commonly cause.So I am at a loss. There is no denying I have been depressed for many years and it has gotten much worse over the last year [hence seeking treatment]. I am not getting any help from these medications and any therapy I have received has been less than helpful. I have an appointment with my doctor tomorrow where I know he is going to ask about how the current medication is working and my answer is obviously going to be that it is not.Does anyone have any idea where he might go next? Theres a good chance he'll opt for a new medication, I'm wondering if anybody has any ideas what it might be. Or if not, where else he might turn.Any advice/input would be appreciated.Thank You.



Antidepressants - What are the options?

I have aspergers and am in college, I went to go see a clinical psychologist without my parent's knowledge under her insurance and got some academic accommodations for school/some counseling. I was on Lexapro in the 3rd grade and was weaned off of that many years ago after being on it for just a few years. Now, as a 20 year old guy, I find my libido has been destroyed by Zoloft! I want this back! Of all things...The last time I saw my doctor, I told her that the benefits outweigh the side effect of the med. It helps me with being more social, relaxed and focused at school. I am calmer without my T level being so high as it is at my age. I had a fight with my mother a month or so ago before the med and I believe it was due to anxieties (I am a biochemistry major) and having a single parent home (the stresses that come with that) and maybe my darned high T level (testosterone). Apparently testosterone isn't affected by this med, but my libido is! It was so high and I kind of enjoyed that part of life. Might as well enjoy it while it is so high!?Here's the costs: It literally costs $6.11/mo for the med (with insurance) and it would only be $73/year to keep having my parent buy the med (but me not taking it). I would take 1 week to wean myself off of it at 25 mg/day. Then go without after that. I just don't want to waste my parent's money. Then there's the $20 copays every 6 months to see the doctor and lie about the med. I just don't want it anymore. Where I live, I also get Seasonal Affective Disorder in the winter. The med helps with this. But I still feel the SAD a little bit. And I hardly have any friends, I do the same routine still. All I feel is numbness in my ***.I hate lying. This morning I got up and got ready for the day and almost had a change of mind. I'm not sure what to do, but think today I'll take 25 mg anyway.* 5 minutes ago* - 4 days left to answer.Additional DetailsI'm pretty sure I felt trembling in my spinal cord after starting to take it a month ago. That was my 'side effect' to start the med. I don't know. I didn't that the med sucked so much and had such side effects. It's a strong SSRI. I talked to the doctor about my 'self pleasuring' practices and she we agreed that it doesn't matter because I'm not sexually active with a partner. She said we could consider quitting it if I become sexually active. She said that she could prescribe Wellbutrin to counteract the med, but I said no due to the added costs ($). Now I change my mind. She said that we could START to consider getting off the med after six months. Why, I don't know.



I want to wean myself off of Zoloft (I have been on it for a month) and am taking 50mg/day?

So this isn't a question against medication for psychological disorders, but rather a question concerning my own history with them. About 4 years ago I started taking Lexapro with mixed results. My doctor soon upped my dosage and then added in Wellbutrin XL for some reason. Later when I switched doctors my new doctor told me to take Celexa instead of Lexapro, get rid of the Wellbutrin altogether (as it did nothing), and then added in Risperdal. That night I took the Risperdal I fell asleep at the dinner table. Soon afterward I switched from Risperdal to Seroquel, added in Ativan, and switched back to Lexapro. Then I switched to Seroquel XR, Klonopin, and stayed on Lexapro. I eventually had to get off Seroquel due to major side effects, and also because it didn't do anything but make me sleepy. I finally had some luck when I stopped taking Lexapro altogether and switched to Zoloft, but it didn't last very long. I also got Xanax and removed the Klonopin at this time. Soon I started taking Adderall with the Zoloft and just got very, very tired for some reason, and then switched to Vyvanse with my Zoloft, which I honestly had the best results with until I was napping 2-3 2 hour naps a day, in addition to my 10 hours at night. Now I am being put on Concerta with my Zoloft, and am just wondering: will this process ever end???


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Lglarsen52 says: January 12, 2011 at 12:07. I take a combination of Wellbutrin & Lexapro & am very pleased with the results. One of the side effects of Wellbutrin is appetite suppression, so you probably will lose weight. ...

Wellbutrin? | Weight Loss Drugs

okay so i'm going to start going on wellbutrin tomorrow.and i just wanted to know what should i expect from the side effects.i have to take it during the day because it causes insomina at night and i'm gonna be at work tomorrow in the ...

Has anyone lost weight on wellbutrin (bupropion) antidepressants ...

Think of it like this. if you follow the instructions on the blog weight loss and muscle building should only take one attempt. Why go through frustrating struggles and risk injury when you can do it the right way. ...

Wellbutrin? | Weight Loss Drugs

I had to stop taking Wellbutrin because my mind was racing so fast I couldn't take it. I couldn't sleep either. If I would've stayed on it I think I would've shot myself. It's horrible. Reply. Freeman says: January 8, 2011 at 21:07 ...

Wellbutrin? | Weight Loss Drugs

It was good that I lost weight, but it sucked for my depression. It was as if it made it worse. I cried all the time for no reason and then cried more because I didnt' know what was wrong with me.It works for some though. ...

Wellbutrin? | Weight Loss Drugs

Reductil / meridia for assisting in weight loss? I want to know about the safety and efficiency of "meridia-sibutramine" + "xenical orlistat" for weight loss? I was just prescribed wellbutrin, seroquel, trazadone, and topamax? ...

Wellbutrin? | Weight Loss Drugs

Alright so i've been taking Wellbutrin since the beginning of June and i was on 100mg till the middle of July. I went up to 150mg because i still wasnt feeling like myself. But now my muscles twitch a lot i can't fall asleep easily. ...

Wellbutrin? | Weight Loss Drugs

Other side effects that are less common but more serious include: palpitations, unusual weight loss or gain, agitation, slowed movements, trouble sleeping, tremor, dizziness, fainting, mood changes, difficulty urinating, drowsiness, ...

Weight loss while taking Wellbutrin XL?

Also - how long does it take before you feel the difference of either drug or lose weight? and how much have you lost? I'm scared to take anything for depression/concentration that will make me gain weight. Thank you.I am clinically depressed and I have refused medication over and over again because I fear altering my state of mind. I feel it is the right thing for me now and I'd like to try it. I do not need to lose weight, but I certainly do not want to gain it - this is why I posted this question. Please respond to the question only if you have an answer that is regarding what was asked. Thank you in advance.I am clinically depressed and I have refused medication over and over again because I fear altering my state of mind. I feel it is the right thing for me now and I'd like to try it. I do not need to lose weight, but I certainly do not want to gain it - this is why I posted this question. Please respond to the question only if you have an answer that is regarding what was asked. Thank you in advance.



What is better for depression, weight loss and concentration? Wellbutrin or Adderall?

I started to take Wellbutrin for depression. After 2 weeks on it, I had to stop. Wellbutrin started to cause major anxiety, nervousness, weight loss, and insomnia. I felt like I was going crazy. I understand the drug gives off tons of adrenaline. Naturally, I always had energy(I'm an athlete). Started Effexor today to help with my anxiety and depression. I hear it is a good medication for my issue but a tough one to come off. Anybody with experience on Effexor. Please share. Also, I hear Effexor is an ok drug for alcohol but could cause craving for it. Thank you!!!!!!!



Wellbutrin to Effexor?

I was prescribed Wellbutrin SR 150 mg 2 and half weeks ago. I want off this drug. First 3 days it worked ok but now, I'm a nervous wreck. Helps with the depression but cannot take the extreme anxiety, insomnia, weight loss, and nervousness. Basiclly, I feel like crap. Not the right medication as I have suffered from extreme anxiety/depression 12 years ago. I look at the Wellbutrin and I do not want to take it. Question is since I have been only on it for 2 and half weeks, would it be safe to quit cold turkey? I do have a doctors apt. in 2 days and hope he puts me on the Effexor as it really really helped me 12 years ago. Thank you!!!!!!!!



Quit cold turkey Bupropion(Wellbutrin SR 150MG)?

I am on Wellbutrin XL 150 mg and have trouble falling asleep even though I am super tired at the end of the day from all the activity I do. Klonopin has caused weight gain although I have had the best results, and I also hear it has high addictive potential (even though I am only taking 0.25 mg so maybe it's not an issue at this low dosage) as a benzodiazepine. Trazodone caused weight loss but not too much, but I ended up feeling more depressed during the day. I even tried a melatonin supplement but over time it ended up slowing me down a lot during the day and I felt depressed too.So is there a way I can deal with the insomnia that the Wellbutrin can bring about? is it possible for me to be able to sleep without some medication? if not, is there a non-addictive drug out there that is ok for long-term usage and doesn't cause weight gain?



any sedative or hypnotic drug I can use to help me sleep?

I am 24yrs old, have bipolar 1 and am taking 40mg of paxil and 2x 100mg of seroquel xr. I have been experiencing weight gain, lost libido, and fatigue. Can my psychiatrist prescribe me phentermine? what about wellbutrin? how effective is wellbutrin for weight loss? is there anything else that would help me?* I am on a low carb, low fat diet and I exercise 4 days a week.



can a psychiatrist prescribe Phentermine?

I am a widow mother of three and work third shift. I am currently in school and battling deep depression. I am taking Wellbutrin XL 300mg for the depression. My weight gain has caused a major problem in my life because it causes me to be isoleted from family and friends. With me crazy life I dont have time to hang out at the gym. What is a good weight loss regimen that I could use to get rid of the excess pounds?



I will like to lose weight and I having a hard time?

I have been on 300 mg of Wellbutrin for about 3 months for depression, and i dont feel like its working as well as something could, so i did some research and reading and found that add medication can sometimes also be used to treat depression/anxiety/weight loss. A friend of mine is on the Wellbutrin as well and has the same symptoms as me, and i am desperate to try anything that might work. (My doctor is also sending me to get tested for add) Anyways... my friend gave me 5 mg dexedrine tablets to try. The first day i took one..didnt feel anything, almost 2 hours later took another one, still nothing...then 4 hours later took one and sort of felt more energized and happy. I've taken in for about 5 days now and havent noticed anything. I was wondering that since i'm on 300 mg of wellbutrin that maybe my tolerance for dexedrine could be higher and maybe i should try a higher dose? this morning i took 2x10mg dexedrine and havent felt anything. Most reviews i've read is that they have felt energized and happy and motivated. but i dont feel any good or bad effects.i feel nothing. I just want to try a dose so that i can see what it will do for me. I've been feeling a little bit more positive but that might just be because i have it in my head that that is what it's supposed to do for you. Could someone please answer or give me some feedback? (please dont talk about the fact that i shouldnt be taking something that isnt prescribed for me) Thank you!



Who is on Wellbutrin and Dexedrine? tips? dosage?

I'm seventeen and, in the past month, I've gained about ten percent of my body weight--from 105 to 115 pounds. The only thing is... This isn't normal! I eat under 1,000 calories a day and burn off about 150 biking (but it's not muscle weight I've gained). My gynecologist was very concerned, and tested my thyroid for the fourth time--again, it's completely normal!My prolactin levels were high, but i'm 90% sure it's just a side effect of my Wellbutrin (which does NOT cause weight gain, usually weight loss).What's going on?? I have never weighed over 110 pounds... I'm only 5'3" and I honestly look like I'm nearly four or five months pregnant. It is uncomfortable and I feel horrible about this weight gain. I know 115 is healthy and 105 is border-line underweight for my height, but I'm not normally this size. Help?



Gained 10% of my body weight in a month--help!?

please help i have severe depression AND anxiety. i also have chronic stomach pains that never seem to go away. i'm getting on a med tomorrow. i am looking for an SSRI. i do not want to gain weight. most antidepressants seem to slow down your metabolism. wellbutrin speeds up metabolism and i would go with that except it causes seizures in a lot of patients. what is a med that wont make me gain weight. a lot of physc meds also cause loss of libio i dont want that either. also i dont want my skin to break out. what is the best antidepressant with lowest side effects that will make u loose weight vs/ gain or do nothing at all. please helpbesides exercise asshole. i already do that.



please help! what is the best antidepressant for what i need?

I had awful time taking Effexor. I had nightmares, shakes and not a good time. I had a horrible withdrawl from it too. Would it be safe to try Wellbutrin? I am a little overweight, so I don't mind the weight loss side effect, but are there any other major ones I should look for?